However, Poland could not weakened confront Turkey, and the world Buchachskomu 1672 gave the Turks a significant part of Podolsk, Kiev Bratslav and provinces. In 1686 Poland regained the land. All XVIII century right bank shake Cossack and peasant uprising. In 1702-1704 years the rebels under the command of Colonel Semen Paliy Fastovsky completely cleared from the gentry and skirts Bratslavschinu. A well-known peasant war of 1768 – Koliivshchina. On the second partition of Poland (1793) Bratslavschina skirts and passed to Russia and formed Podolia. In the western part of the province included Podolia province, in eastern – Bratslav.
Vineyard became the provincial town, but later transferred to the state district of the city (the administrative center of the province was Kamenetz). In 1798, the city introduced "city regulations." In 1860 the winery is home to 10 thousand inhabitants, there were 5 schools, hospital, theater, and 190 stores. An important stimulus to the development of Vinnitsa is the building in 1870 near the city railway Kiev-Odessa-Balta, through which much improved communication with Kiev, Odessa, Moscow, St. Petersburg. Over the past 40 years of the XIX century Vinnitsa increased in three and a half times, and on turnover came in first place in Podolia.
Since 1914 Vinnitsa – the administrative center of Podolia. October 28, 1917 in Vinnitsa, an armed uprising, as a result of whose power in the city went to the revolutionary committee of workers and soldiers. Later during the Civil War, the power in the city repeatedly passed from hand to hand. In the city some time to work Government of the Ukrainian People's Republic. Finally, the Soviet authorities in the winery was established in 1920. In 1923, Vinnytsia became the county seat, and since 1932 the administrative center of Vinnitsa region. After the start Great Patriotic War, thousands of vinnichan went to the front. To combat with the enemy saboteurs and safety of industrial facilities has been created destroyer battalions.